West Indies has never won a test series against South Africa.
| Series/Tournament | Season | Winner | Margin |
|---|---|---|---|
| South Africa in West Indies Test Match | 1991/92 | West Indies | 1-0 (1) |
| West Indies in South Africa Test Series | 1998/99 | South Africa | 5-0 (5) |
| Sir Vivian Richards Trophy (South Africa in West Indies) | 2000/01 | South Africa | 2-1 (5) |
| Sir Vivian Richards Trophy (West Indies in South Africa) | 2003/04 | South Africa | 3-0 (4) |
| Sir Vivian Richards Trophy (South Africa in West Indies) | 2005 | South Africa | 2-0 (4) |
| Sir Vivian Richards Trophy (West Indies in South Africa) | 2007/08 | South Africa | 2-1 (3) |
| Sir Vivian Richards Trophy (South Africa in West Indies) | 2010 | South Africa | 2-0 (3) |
| Sir Vivian Richards Trophy (West Indies in South Africa) | 2014/15 | South Africa | 2-0 (3) |
| Sir Vivian Richards Trophy (South Africa in West Indies) | 2021 | South Africa | 2-0 (2) |
| Sir Vivian Richards Trophy (West Indies in South Africa) | 2022/23 | South Africa | 2-0 (2) |